Does plaquenil lower immune system

Discussion in 'Aralen 250 Mg' started by AIKON, 03-Mar-2020.

  1. Walery User

    Does plaquenil lower immune system


    I started on it just less than 2 weeks ago, and I'm surrounded by ill people at work and already have a bit of a cold (nothing severe). it is "milder" than a lot of the other dmards in terms of side effects and activity x It is listed as having a mild immunosuppressant effect in my book on RA, but one of the reasons for the blood tests is to check that your immune system is not being suppressed too much (eg checking your white blood cell levels), so you shouldn't be completely vulnerable. Even after several years of taking lots of drugs I've not found any difference in the number of colds etc I get, and loads of people on here are teachers etc who get a lot of exposure to colds and coughs without too much problem.

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    I started on plaquenil about 3-4 yrs ago and now the last two yrs I've gotten sick several times. They use plaquenil to suppress your immune system to slow it down, not speed it up. Your system is working overtime, so IMO, its stronger and that causes the problems we have the body needs a nice nuetral immune system working normally. Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation. There is evidence that hydroxychloroquine may interfere with communication between cells in the immune system. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus.

    Polly Thank you both, I thought it shouldn't be too bad and that it's pretty mild in comparison to other drugs. Always better to be well informed and I remember the consultant saying its bit a bad time of year to start on it as I've missed all the bugs round Christmas time so thought there may be a slim chance of it being suppressed. But do look after yourself, and make sure you eat well and don't get too tired as if you have a cold already you need to pamper yourself a bit more than you would have before RA.

    Does plaquenil lower immune system

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  7. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as.

    • Plaquenil Hydroxychloroquine - Side Effects, Dosage..
    • Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus.
    • Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus..

    I usually start with a low dose of 100-200 mg per day to help the patient adapt to the medicine and allow an increase in dose later to as high as 300-400 mg per day. Less common adverse effects of Plaquenil are drug-induced skin rashes. These rashes may consist of many small red bumps or bright red skin covering most of the body. Mar 23, 2014 I doubt it is the Plaquenil affecting your immune system, but the actual Lupus itself as it can affects the white blood cells and lower them so we get every infection going. You need to speak to your rheumy for more clarification in your case. Feb 04, 2015 I have been taking plaquenil for almost a year, does this drug lower your immune system's effective? Asked by fredkintner Updated 4 February 2015 Topics

     
  8. Lesh_a User

    Hydroxychloroquine is widely used in the treatment of post-Lyme arthritis. Hydroxychloroquine - LiverTox - NCBI Bookshelf Chloroquine MedlinePlus Drug Information Chloroquine - FDA prescribing information, side effects.
     
  9. I don't know if anyone can help as this isn't technically lupus related. Let me tell you what weaning down from Plaquenil is like. Stopping Plaquenil - General Discussion - Life With Lupus Will you have Withdrawal syndrome with Plaquenil - eHealthMe
     
  10. Russss Guest

    Hydroxychloroquine Oral Tablet 200Mg Drug Medication Dosage Information Hydroxychloroquine Oral tablet 200mg Drug Medication Dosage information. Learn about the reported side effects, related class drugs, and how these medications will affect your daily lifestyle.

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.
     
  11. odin_ac Well-Known Member

    Plaquenil Uses, Dosage & Side Effects - Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared.

    Plaquenil Use in Autoimmune Diseases