Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Biaxin plaquenil lyme Hydroxychloroquine alcohol interaction A baseline eye examination is recommended prior to starting EMB to document pre-existing ocular pathology and baseline visual field testing. Patients on EMB should be risk stratified with high risk patients e.g. high dose 15 mg/kg, long duration, other ocular co-morbidities, vitamin deficient, or renal failure being evaluated monthly. Irreversible retinal damage observed in some patients who had received hydroxychloroquine sulfate; significant risk factors for retinal damage include daily doses of hydroxychloroquine sulfate greater than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than five years, subnormal glomerular filtration. Hydroxychloroquine retinopathy is most influenced by daily dose and duration of use. Risk for toxicity is less with 5.0 mg/kg real weight/day for hydroxychloroquine and 2.3 mg/kg real weight/day for chloroquine. Patients are at low risk during the first 5 years of treatment. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil mg kg eyewiki Scleromalacia Perforans - EyeWiki, Plaquenil hydroxychloroquine sulfate dosing, indications. Plasmodicidal action of chloroquinePlaquenil maculopathy oct of maculaPlaquenil depression side effectsHydroxychloroquine sulfate and pregnancyColor perception changes in plaquenil Doses ≥ 5 mg/kg/day real weight of hydroxychloroquine 2.3 mg/kg/day of chloroquine are associated with higher risk of toxicity. Doses lower than 5 mg/kg/day have low risk 1% for the first 5 years, and below 2% between 5-10 years of use. The longer you use. Hydroxychloroquine And Chloroquine Screening 2016 AAO.. Hydroxychloroquine toxicity - EyeWiki. Plaquenil Dosage Guide -. Mg/kg 5 mg/kg base of actual body weight, subnormal glomerular filtration rate, durations of use longer than five years, and concurrent treatment with tamoxifen citrate. Concomitant use of PLAQUENIL with drugs known to induce retinal toxicity, such as tamoxifen, is not recommended. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules Dosing is usually much lower in children and infants depending on their body weight, usually 5 mg, calculated as base, per kilogram kg of body weight one 200 mg tablet = 155 mg base.