Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Rheumatoid arthritis hydroxychloroquine medications Plaquenil and syncope Plaquenil and magnesium Dec 15, 2004 Multifocal ERG has a consistent topographic distribution in the normal population. However, the summed amplitude of multifocal ERG can vary significantly among normal subjects. Therefore, topographic abnormalities via a three-dimensional distribution map are useful for the interpretation of multifocal ERG in diseased patients. Aetna considers multi-focal ERG mfERG medically necessary for detecting chloroquine Aralen and hydroxychloroquine Plaquenil toxicity. Aetna considers multi-focal ERG experimental and investigational for all other indications including the following not an all-inclusive list Diagnosis/evaluation of glaucoma With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil erg The Electroretinogram and Electro-oculogram Clinical., Electroretinography - Medical Clinical Policy Bulletins Aetna Plaquenil eye dosageArthritis medication hydroxychloroquineCan you take plaquenil as needed Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. New Plaquenil Guidelines -. Early Plaquenil Toxicity Detected without Bull’s Eye.. This is Why You Need Multifocal ERG if You Have Plaquenil Patients. To detect chloroquine toxicity. Which type of ERG to apply depends on the mechanism and site of retinal toxicity. Identifying retinal toxicity due to chloroquine or hydroxychloroquine is a pertinent application of mfERG. Plaquenil toxicity first affects small areas of the retina between 5° and 15° from the fovea. Figures 2 and 3 show. Dr. Marmor said, “We also recommend use of objective tests such as spectral domain OCT, multifocal ERG and fundus autofluorescence.” He added that older time domain OCT units lack enough sensitivity for Plaquenil toxicity. Go by ideal, not real, weight. Dr. A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to.