Chloroquine dosing for lupus

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  1. diannna New Member

    Chloroquine dosing for lupus


    Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

    Chloroquine trade name generic name Plaquenil malaria prevention

    Adults 250 mg P. O. daily chloroquine phosphate with evening meal. Lupus erythematosus. Adults 250 mg P. O. daily chloroquine phosphate with evening meal; reduce dosage gradually over several months when lesions regress. Pharmacodynamics Antimalarial action Chloroquine binds to DNA, interfering with protein synthesis. It also inhibits DNA. In active rheumatoid arthritis and systemic and discoid lupus erythematosus, to avoid excessive dosage in obese patients, the daily maximum dose should be calculated on the basis of ideal body weight. For treatment of amebiasis, one dose is usually taken for 2 days and then half the dose every day for 2 to 3 weeks. It is usually taken in combination with other amebicides. Chloroquine phosphate may cause an upset stomach.

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Chloroquine dosing for lupus

    An Update on Treatment and Management of Pediatric., CHLOROQUINE Drug BNF content published by NICE

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  6. This represents a total dose of 2.5 g Chloroquine phosphate or 1.5 g base in three days. Infants and Children In infants and children, the recommended dose is 10 mg base/kg followed by 5 mg based/kg at 6, 24 and 36 hours total dose 25 mg based/kg.

    • Chloroquine - FDA prescribing information, side effects..
    • Chloroquine MedlinePlus Drug Information.
    • Hydroxychloroquine Dosage Guide with Precautions -.

    A cumulative dose of over 460 g or a daily dose of 2.3 mg/kg body weight/day is high risk. The latest studies show that using the patient's real weight instead of ideal weight correlates better with safe dosing. Chloroquine is rarely an option for rheumatic diseases over hydroxychloroquine. Systemic lupus erythematosus is a disease that continues to evolve over time. Thus, a patient who presents with skin and joint disease remains at risk for renal disease even after having lupus. Mar 17, 2019 Hydroxychloroquine dosing information. Usual Adult Dose for Malaria Treatment of the acute attack 800 mg 620 mg base followed in 6 to 8 hours by 400 mg 310 mg base, then 400 mg 310 mg base once a day for 2 consecutive days; alternatively, a single dose of 800 mg 620 mg base has also been effective

     
  7. Shooter Guest

    Atovaquone/Proguanil (Malarone) Adults: 1 adult tablet daily. Mefloquine Dosage Guide with Precautions - Chloroquine-Resistant Malaria in Travelers Returning from. Chloroquine - Wikipedia
     
  8. RCDL2006 Guest

    Hydroxychloroquine - Wikipedia One of the most serious side effects is a toxicity in the eye generally with chronic use. People taking 400 mg of hydroxychloroquine or less per day generally have a negligible risk of macular toxicity, whereas the risk begins to go up when a person takes the medication over 5 years or has a cumulative dose of more than 1000 grams.

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