It is a disabling and painful condition which can lead to substantial loss of mobility due to pain and joint destruction. I've been off it a few days and thankfully my plumbing is back to normal it seems and the huge acne has stopped/gone. The disease is also systemic in that it often also affects many extra-articular tissues throughout the body including the skin, blood vessels, heart, lungs, and... Since I'm a woman I managed to bypass the plumbing problems while on the prednisone (I'm on 30 mg), but you're right, the acne is BAD!! Considering the state my joints are in though, I suppose that's the least of my problems. Hydroxychloroquine making my body go to sleep Antipaludéen de synthèse plaquenil Health related message boards offering discussions of numerous health topics including allergies, cancer, diabetes, heart disease, exercise, attention deficit disorder, diet, and nutrition. Lupus Board Index how long does it take plaquenil to work Weight-bearing exercise forces you to work against gravity, placing stress on the bones. Autoimmune diseases, like rheumatoid arthritis and lupus, are linked. Facts for patients and caregivers about the DMARD drug Hydroxychloroquine Plaquenil such as usages, Today, it is used to treat rheumatoid arthritis, Feb 09, 2012 Plaquenil is actually a treatment for malaria but when given to patients with Lupus the patients improved. Over the long term the medication protects your blood vessels which reduces long term complications. I have had Lupus for 23 years. Eventually the side effects abate. It should also help with joint and muscle pain. My doctor was only able to find it after I requested a MRI of my hands. Of course neither has the prednisone, sulfasalazine, or methotrexate. Hi guys, I was diagnosed with RA in April 08 and I'm 29 years old. I've been on plaquenil for over 4 months and it hasn't done squat for me. How long does it take plaquenil to work for lupus How is plaquenil hydroxychloroquine used to treat lupus?, How Does Plaquenil Work For Rheumatoid Arthritis Chloroquine for transductionWhy does chloroquine itch Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Systemic Lupus Erythematosus - Does anyone else take.. Plaquenil. A medication for Lupus. It does not work against certain. It may take several weeks or months to see improvement if you are taking this for lupus or arthritis. Hydroxychloroquine may not prevent malaria in all cases. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. How long does it take for plaquenil to work? I just started about 6 weeks ago, the rheum said it can take up to a year. I just started about 6 weeks ago, the rheum said it can take up to a year. Let me know how you are doing on it!