Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil dilated eye retinal exam Saliva drug test rx hydroxychloroquine false positive drug test Is there a drug interaction between inruprofen and plaquenil Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. With Plaquenil Plaquenil is manufactured in only a 200 mg tablet The typical dosage is either 200 or 400 mg per day 200 mg daily puts anyone under 68 pounds at risk1 400 mg of Plaquenil daily puts anyone under 135 pounds at a higher risk for toxicity Therefore, 200mg of Plaquenil daily is going to be a safe dosage for virtually all adults13 Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil corneal deposits Plaquenil Related Eye Problems - Fraser Eye, Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy Chloroquine diphosphate storage The cornea may become affected relatively commonly by an innocuous vortex keratopathy and is characterized by whorl-like corneal epithelial deposits. These changes bear no relationship to dosage and are usually reversible on cessation of hydroxychloroquine. PLAQUENIL hydroxychloroquine and the Eye Westford. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Rx Side Effects New Plaquenil Guidelines and More.. B. Cornea Transient edema, punctate to lineal opacities, decreased corneal sensitivity. The corneal changes, with or without accompanying symptoms blurred vision, halos around lights, photophobia, are fairly common, but reversible. Corneal deposits may appear as early as three weeks following initiation of therapy. Prolonged indomethacin treatment is associated with corneal deposits and retinopathy bull's eye maculopathy. These ocular pathologies were reported in a small series of patients, 26 but Bernstein found corneal deposits in approximately 18% of patients in a long-term study. 6. 2.1.6. Additional cationic amphiphilic drugs Sulfasalazine. The reports on ocular side effects from the usage of sulfasalazine are relatively few, despite its commercialization for a long time; the drug is generally considered safe and well tolerated. 47 There has been a report of peripheral facial nerve palsy and blurred near vision in association with sulphasalazine treatment. 48 Santodomingo et al. 49 presented a sudden bilateral.