It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Cost of chloroquine and proguanil Plaquenil macular damage Aug 07, 2018 Subacute cutaneous lupus erythematosus SCLE is a nonscarring, non–atrophy-producing, photosensitive dermatosis. SCLE commonly develops in sun-exposed areas, including the upper back, shoulders, extensor arms, neck, and upper torso, while the face is often spared. Cutaneous lupus erythematosus CLE is the second most common presenting symptom of autoimmune lupus erythematosus LE. Lesions precede the onset of systemic symptoms in 25 percent of patients, many of whom present to dermatologists for their initial evaluation.1 Prompt diagnosis of CLE requires a thorough understanding of the cutaneous manifestations and clinical spectrum of lupus. Subacute cutaneous lupus erythematosus SCLE is a clinically distinct disease that is associated with systemic lupus erythematosus in 50% of patients, and can be associated with Sjögren’s syndrome and patients with a deficiency in the second and fourth components of complement. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Scle plaquenil Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Treatment of Cutaneous Lupus Erythematosus Plaquenil sjogrens syndromeIs generic plaquenil as goodHydroxychloroquine autophagy pancresPlaquenil oct scanCan plaquenil cause gingivitis in humans Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Subacute Cutaneous Lupus Erythematosus - American Osteopathic.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Medscape - Indication-specific dosing for Plaquenil hydroxychloroquine sulfate, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Ideal body weight is calculated as follows 45.5kg use 50kg for males + 2.3 kg for each inch over 5 feet; or 45.5kg + 2.3kg * height inches-60. Antimalarials take 2 to 3 months for improvement to be noticed and up to 6 months for a complete response.