If so, would you share a comment on the experience you have had with methotrexate; & the length of time on the medication, benefits noted, and side effects. It can be brief or as detailed as you desire to describe your experience. I used plaquenil for some time on its own, then added in MTX before changing over to leflunomide. Ranitidine and plaquenil Plaquenil diarrhea Plaquenil hydroxychloroquine "I have been on this medication for approximately 8 years. Before I started this medicine I was in terrible shape. With Sjogren's syndrome as my primary autoimmune disease and rheumatoid arthritis as my secondary autoimmune disease I was in terrible persistent pain. Jul 19, 2010 Methotrexate is a common medication that is prescribed to patients diagnosed with Sjogren’s syndrome and other autoimmune diseases. Methotrexate replaced the more powerful and toxic antifolate aminopterin starting in the 1950s. Dec 27, 2017 · Methotrexate The blog of the Sjogren's Syndrome Foundation covering all aspects. Methotrexate The blog of the Sjogren's Syndrome Foundation covering all aspects of Sjogren's and its symptoms. is poorly controlled with non-steroidal anti-inflammatory drugs NSAIDs, low doses of steroids and Plaquenil hydroxychloroquine are often. I would have stayed on MTX if it worked for me, but it didn’t. I didn’t drop plaquenil until I had been on a biologic for about six months. Plaquenil and methotrexate for sjogren's syndrome Methotrexate opinions - Symptoms and Medical Treatments., Sjogren's Syndrome Methotrexate Hydroxychloroquine and folic acidEasy bruising plaquenil reddit Sep 05, 2016 I think the Plaquenil is still helping me, but for whatever reason my Sjogren's is just getting more aggressive lately. If a doctor wants to give you a medicine, then they think it might help you. You should at least give it a try. There is no "cure" for Sjogren's at least not yet and medicine won't magically make all your symptoms go away. Plaquenil - General - Sjogren's Syndrome Support. Conquering Sjogren's Methotrexate. Ask the Expert Plaquenil and Sjögren’s. Sjogren’s syndrome can affect all moisture-producing glands and tissues in the body – not just the eyes and mouth – and cause a host of symptoms. Below is head-to-toe a look at over-the-counter and prescription treatment options, as well as some medical procedures, for this common autoimmune condition that affects nine times as many women. NSAIDS - or non steroidal anti inflammatory drugs such as Motrin, are often very irritating to the stomach and intestines. Other medications frequently used in treating Sjogren's Syndrome such as Plaquenil and Methotrexate may cause stomach upset. Does anyone use methotrexate just for their Sjogrens symptoms? If so, would you share a comment on the experience you have had with methotrexate; & the length of time on the medication, benefits noted, and side effects. It can be brief or as detailed as you desire to describe your experience. Thank you. Oh!