I have been on plaquenil for over a year and a half and methotrexate since September. I get my eyes checked every six months and I am now at once a month on blood work for my liver enzymes (used to be every 2 weeks). I have lupus which mainly affects my joints and skin. One affects your eyes more and one affects your liver more. I would appreciate any comments or advice from everyone. Wannabe Hi, I am on both methotrexate and plaquenil. Wannabe To Be Free To Roam Sorry to hear that you are having a lot of pain with your RA. Que es el plaquenil What class of drug is hydroxychloroquine sulfate OBJECTIVE To examine the bioavailability of methotrexate MTX in the presence of hydroxychloroquine HCQ, and vice versa, to determine a possible pharmacokinetic explanation for the observation that combination treatment of rheumatoid arthritis with MTX and HCQ has been shown, clinically, to be more potent than MTX used alone. If you aren’t responding to methotrexate after a two-month period, your rheumatologist may try some kind of combination therapy, such as adding sulfasalazine and hydroxychloroquine called triple therapy or adding a biologic drug such as etanercept Enbrel, adalimumab Humira, or infliximab Remicade. Patients whose arthritis is poorly controlled with non-steroidal anti-inflammatory drugs NSAIDs, low doses of steroids and Plaquenil hydroxychloroquine are often managed with methotrexate. Methotrexate is usually taken just once a week in tablet form. Some patients take it as a weekly injection. I wish you well with this decision and the results. Your chances of problems with the methotrexate are a bit larger. deductible (I am at about $2,500 - $3,000 right now). My rheumy recently added Imuran (instead of methotrexate). So, what do yall know about the side effects of both and the benefits of both? Methotrexate and hydroxychloroquine Treatment of Rheumatoid Arthritis with Methotrexate Alone., Common Questions About Taking Methotrexate for Rheumatoid Arthritis Plaquenil and weight gain forumPlaquenil dilated eye retinal examChloroquine in cancer therapy a double edged sword of autophagyChloroquine phosphate synthesis We aimed to compare the efficacy of methotrexate and hydroxychloroquine on refractory lichen planopilaris. Methods In a randomized clinical trial, 29 patients were randomly allocated to receive either 15 mg methotrexate/week or 200 mg hydroxychloroquine twice a day for 6 months. Clinical efficacy and safety of methotrexate versus hydroxychloroquine.. Methotrexate and its benefit for Sjögren’s patients. Effects of methotrexate and hydroxychloroquine combination.. Hi everyone! I'm a fairly new methotrexate and hydroxychloroquine user started both in mid-December of last year and am due to go on holiday in Florida on Saturday. There have been a number of coronavirus cases in Florida and two deaths there from the illness. Being on immunosuppressants I'm a little nervous to be travelling there. Curcumin in turmeric may increase the therapeutic action of arthritis medications and protect from their side effects as well. Let’s examine the scientific details behind the safety of taking turmeric and curcumin with arthritis medications. 1. Curcumin may change drug absorption. Turmeric and curcumin are safe for consumption. Compare Methotrexate vs Plaquenil head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Plaquenil rated 6.8/10 in overall patient satisfaction.