After the fevers I get severe chilblains on my fingers, ears and toes. This I have always attributed to the Raynauds I was diagnosed with as a child. Plaquenil low dose Sigma chemical chloroquine phosphate Oct 22, 2019 In 2002 I got a new doctor that diagnosed me with SLE and started me on plaquenil. I don't remember exactly how long it took but after some months the fever went down. I have always had fatigue after my first flare and joints and muscle pain every day along with many respiratory infections and skin rashes. But the fever has stayed away. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. May 05, 2010 I don't know if this is just the RA in full swing, or if it is a side effect of the Plaquenil. I have been running a low-grade fever around 99.8 for about. a week and a half now. It comes & goes and I can tell when it is up because I feel hot. My normal body temperature is low, around 97.5, so I don't know if 99.8 would be considered a fever. So the reason for the post is to know if anyone here has had similar issues with unexplained fevers that cause chilblains? They typically form in the evenings and hurt like hell. It very mild case that is actually more sensitive to heat then cold. When i went off plaquenil i got fevers Immune & Autoimmune - Lupus should I take Plaquenil now or wait?, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Chloroquine and tonic waterHydroxychloroquine inrPlaquenil labsPlaquenil for arthritisHydroxychloroquine making my body go to sleep But I was just gonna tell you that I was on Plaquenil for quite a while, it was not until I got off for about 4 months that I began to lose chunks of hair. So I did get back on the Plaquenil and got the hair and inflammation lined back out and then I tapered the plaquenil down to 200mg when I was originally on 400. Hair loss and Plaquenil? DailyStrength. Does Plaquenil cause fatigue or fever? - Rheumatoid Arthritis. Plaquenil, a warning. lupus. Hi. I had been taking Plaquenil for about three years. Six months ago the doctor put me on the Imuran. I did not have any side effects from it thank goodness. Unfortunately, I had to stop taking it just last week. Every time I would get sick I would have to stop taking it. It lowered my immune system so much that I caught anything going around. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. May 05, 2016 Plaquenil was originally developed in the 1940's and used most often for treating or preventing malaria, which is spread by mosquitoes and can cause fever, chills, and a flu like illness.