Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Arthritis medication hydroxychloroquine What is hydroxychloroquine for Common side effects Nausea and diarrhea This can often can be combatted by taking Plaquenil with food or milk. Dizziness Precautions with this side effect Do not drive, use machinery. Cramps. Headache. Dry skin. Loss of appetite. Compare Plaquenil vs. Prednisone, which is better for uses like Lupus, RA and Sjogren's Syndrome. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Plaquenil 3.7/5 over Prednisone 3.2/5 in overall satisfaction. Serious side effects. blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. blue-black skin color. muscle weakness. hair. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil and prednisone side effects Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil vs Prednisone - Posts about Drugs, Side effects. Optometry plaquenil dosage retinopathy Plaquenil and Prednisone is not even in the same class of drugs. The prednisone is a steriod and the plaquenil is a anti malaria drug. The thing with plaquenil for me is that I don't notice much of anything taking it but when I go off then I flare up and then really notice it. Prednisone and Plaquenil DailyStrength. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil vs Prednisone Comparison -. But you can’t even compare it to the only other things I have to treat lupus—prednisone, where 100 percent of people get side effects, or immunosuppressive drugs, which suppress the immune system, potentially causing infections, low blood counts, and liver toxicity. The Stranger Side Effects of Prednisone. Prednisone is a prescribed medication that reduces swelling, irritation, and inflammation in the body for a range of conditions. While this powerful steroid drug is helpful for many, it also packs a variety of side effects, including restlessness, weight gain, and irritability. My question Do you feel like you've gained weight on Plaquenil ie without Prednisone? The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead. The Plaquenil drug side effects list weight loss, but some people have reported weight gain instead.