Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine and tlr signaling Chloroquine sulphate structure Plaquenil perte cheveux Chloroquine in lentiviral transduction Vitamin B12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations. Screening average-risk adults for vitamin B12 deficiency is. Incidentally, I asked him why plaquenil causes hair loss, and he said no one knows why. It's just one of those drugs known to have that side effect. Nothing to really help it he said, other than taking folic acid, b12 and biotin. I asked him about methotrexate, and he said he was on it for years for his RA and never had any major side effects. Vitamins with plaquenil and pred. B6 and B12 for the MTHFR gene. I think it is fine b.c I am also on both and the docs really want me on a good multi vit. Hope. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and b12 Plaquenil Hydroxychloroquine - Side Effects, Dosage., Let me tell you what weaning down from Plaquenil is like. Hydroxychloroquine sulfate davisChloroquine in lepra reaction Annual screening may be commenced before 5 years of treatment if additional risk factors for retinal toxicity exist, such as concomitant tamoxifen therapy, impaired renal function eGFR less than 60 mL/minute/1.73 m 2 or high-dose therapy greater than 5 mg/kg/day of hydroxychloroquine sulfate. HYDROXYCHLOROQUINE SULFATE Drug BNF content published by NICE. Vitamins with plaquenil and pred. DailyStrength. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Two days now I've taken the Pepcid, then an hour later took the Plaquenil and it's working great. I didn't even eat this morning and didn't have a problem. BTW I talked to two pharmacists and both said that it's okay to take with the plaquenil. Anemia, serum vitamin B12, and folic acid in patients with rheumatoid arthritis, psoriatic arthritis, and systemic lupus erythematosus. Segal R1, Baumoehl Y, Elkayam O, Levartovsky D, Litinsky I, Paran D, Wigler I, Habot B, Leibovitz A, Sela BA, Caspi D. Hydroxychloroquine may improve symptoms of rheumatoid arthritis symptoms in roughly half a year. If you use this medication and your symptoms don’t improve in that time window, or if they get worse, experts at the National Institutes of Health recommend that you discontinue the medication and call your physician.