Treatment of discoid lupus erythematosus with chloroquine

Discussion in 'Cheap Chloroquine' started by SAKYRA, 29-Feb-2020.

  1. Acedofiline Guest

    Treatment of discoid lupus erythematosus with chloroquine


    Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality.

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    Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Oral thalidomide has increasingly been accepted as a treatment for cutaneous lupus erythematosus CLE, including DLE lesions, that have not responded to other treatments. Stevens RJ, Andujar C, Edwards CJ, et al. Thalidomide in the treatment of the cutaneous manifestations of lupus erythematosus experience in sixteen consecutive patients. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Important information. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye.

    Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids.

    Treatment of discoid lupus erythematosus with chloroquine

    Discoid Lupus Erythematosus Treatment & Management Approach., Discoid lupus erythematosus - Treatment algorithm BMJ.

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  5. Hydroxychloroquine and chloroquine with or without quinacrine are currently utilized in the treatment of discoid lupus erythematosus. Hydroxychloroquine is preferred over chloroquine due to the lower risk of side effects, specifically retinal toxicity. Thalidomide, a potent teratogen, has been used in the treatment of discoid lupus erythematosus.

    • Discoid lupus erythematosus causes, signs, symptoms..
    • Hydroxychloroquine Uses, Dosage & Side Effects -.
    • Discoid lupus erythematosus Symptoms and treatment of..

    Two cases of subacute disseminated lupus erythematosus were also treated with chloroquine sulphate with no satis-factory clinical response. Summary and Conclusions Eighteen cases of chronic discoid lupus erythematosus were treated with chloroquine sulphate by mouth. The results are tabulated and discussed. Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus CLE. Although new recommendations exist for hydroxychloroquine dosing, there is still uncertainty about the dosage that will elicit a satisfactory response in CLE while limiting adverse effects, specifically retinopathy. Immunofluorescence of immunoglobulin G, immunoglobulin M, immunoglobulin A, and complement demonstrates a positive lupus band test. This occurs predominantly in the basement membrane and is found in the clinically uninvolved non–sun-exposed skin. Treatment for discoid lupus includes steroids and antimalarial drugs such as hydroxychloroquine.

     
  6. spider7 Guest

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Hydroxychloroquine Plaquenil Common Plaquenil side effects a study from FDA data - eHealthMe
     
  7. pavvloff Guest

    El aralen (cloroquina) es un medicamento creado para tratar el paludismo, pero se le ha encontrado la capacidad de regular la respuesta inmunológica responsable de a inflamación en enfermedades como la artritis, el lupas y otras. Aralen Oral Uses, Side Effects, Interactions, Pictures. ARAVA - PLM Aralen - Información del medicamento, indicaciones, efectos.
     
  8. insomnia XenForo Moderator

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. The recommended adult dosage is 200 to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. Doses above 400 mg a day are not recommended. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded.

    Plaquenil Oral Uses, Side Effects, Interactions, Pictures.
     
  9. Bazalai User

    Plaquenil Uses, Dosage & Side Effects - Apr 10, 2019 Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye.

    Plaquenil - FDA prescribing information, side effects and uses