It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Plaquenil and weight gain forum Chloroquine for fish ich I have mild SLE and only take 200mg once a day. I'm 5'3" and weigh 10st 10lb so I'm overweight. I also have hashimotos so losing weight is very hard! I walk 5 miles a day and watch what I eat but short or starving myself then. Anyway when I started taking hydroxychloroquine I noticed hyperpigmentation starting. Nov 25, 2019 Usual Adult Dose for Systemic Lupus Erythematosus. Initial dose 400 mg 310 mg base orally 1 to 2 times a day; this dose may be continued for several weeks or months, depending on patient response Maintenance dose 200 to 400 mg 155 to 310 mg base orally daily Comments-Each dose should be taken with a meal or a glass of milk. Jan 03, 2020 The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. In a small percentage of patients, side effects may require temporary reduction of the initial dosage. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Sle hydroxychloroquine dose Hydroxychloroquine Oral Uses, Side Effects, Interactions, Pictures., Hydroxychloroquine Dosage Guide with Precautions - Chloroquine-primaquine-phosphate. Mar 17, 2019 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking this medicine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Hydroxychloroquine Uses, Dosage & Side Effects -. Plaquenil Dosage Guide -. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. The researchers suggest that Plaquenil, “ should be considered as a therapeutic option in all patients with SLE and should be administered using established guidelines so that the proper dose is prescribed not exceeding 6.5 mg/kg of ideal body weight and adequate ophthalmological monitoring is performed.” The safety and efficacy of the chronic use of hydroxychloroquine for systemic lupus erythematosus and juvenile idiopathic arthritis in children and infants have not been established. Children are especially sensitive to the 4-aminoquinoline compounds.