Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Plaquenil rheumatoid arthritis dosage Chloroquine define Chloroquine scheduled drug I can't say for sure if plaquenil would slow down or halt progression of RA, but I've been told methotrexate does. As for a comparison between the two, it's difficult to say. As long as you have regular eye doctor appointments and blood tests to check for adverse reactions, you'd be able to catch anything bad ahead of time before significant. Regular eye exams give your eye care professional a chance to help you correct or adapt to vision changes and provide you with tips on caring for your eyes. When to have an eye exam Several factors may determine how frequently you need an eye exam, including your age, health and risk of developing eye problems. Plaquenil is the one drug that you need the eye exam prior to starting the drug as they really need that baseline. If it's going to affect your eyes, tends to do so in the first 6 months. but I don't think MTX is the same.doc hasn't made me get it prior to treatment but he is adamant about yearly eye exams. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Plaquenil eye exam same as regular eye exam Plaquenil Side Effects on Your Eyes and Vision, Eye exam - Mayo Clinic Would chloroquine in a sickle cell patient be harmful Both my rheumatologist and opthamologist recommended exams every 6mo for the first year I was on plaquenil. Now I just go yearly to have my eyes checked. Also, my rhuemy said any time he makes an adjustment to my plaquenil that I'll need an eye exam within 6mo just to make sure nothing has changed. Plaquenil and eye exams" Lupus Community - Support Group. Bone Joint Muscle - Arthritis Baseline eye exam and Methotrexate. Has anyone experienced plaquenil toxicity with damage to eyes?. Apr 10, 2019 Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. I went to my rheumy appt and after 1hr 45 min later all had agreed it was the plaquenil. The strange thing is it had only affected the r eye. And yes i did have a baseline eye exam in oct before i started and then this one after experiencing the pain and pressure. Dec 21, 2017 Rheumatoid Arthritis and Your Eyes Watch Out For These Complications. When using Plaquenil, it is recommended to get regular eye exams every six months to catch early changes in the retina.