What is the process of making chloroquine

Discussion in 'Chloroquine Phosphate' started by beee, 22-Feb-2020.

  1. Bazileus Guest

    What is the process of making chloroquine


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    Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. Chloroquine contains the lysosomotropic character that is believed to account for much of its antimalarial activity; the drug concentrates in the acidic food vacuole of the parasite and interferes with essential processes. It is so dangerous because it contains toxic to cure malaria and amebiasis. Chloroquine is used to prevent and treat malaria. It is also used to treat liver infection caused by protozoa extraintestinal amebiasis. Chloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito.

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    What is the process of making chloroquine

    From chloroquine to artemether-lumefantrine the process of., The synthetic process used to make Chloroquine -

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  6. Nov 15, 2015 However, note that Chloroquine has other properties as well that may be very well related to anti cancer mechanism, such as zinc ionophore, and others see below the section on mechanisms. In cancer, authophagy is the process used by cancer cells to “self-eat” in order to survive. This is why authophagy can be both good and bad.

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    Sep 15, 2009 Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain Daniel P. Iwaniuk, 1 Eric D. Whetmore, 1 Nicholas Rosa, 1 Kekeli Ekoue-Kovi, 1 John Alumasa, 1 Angel C. de Dios, 1, 3 Paul D. Roepe, 1, 2, 3 and Christian Wolf 1, 3 Chloroquine CQ is an important antimalarial drug for the treatment of special patient groups and as a comparator for preclinical testing of new drugs. Mixing together eggs, flour, sugar, water and other ingredients to make dough, then baking that dough in an oven, can seem like a simple yet magical process. The delicious end result that appears accentuates the extraordinary nature. It's not magic, however, but a series of complex chemical reactions that is.

     
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    Accumulating evidence suggest that autophagy plays a pivotal role in various anticancer therapies, including photodynamic therapy (PDT), acting as a pro-death or pro-survival mechanism in a context-dependent manner. Anti-LC3-I/II Antibody Sigma-Aldrich Autophagy Made Visible - Thermo Fisher Scientific Phenotypic Profiling of Autophagy - PerkinElmer
     
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    AAO Screening Guidelines for Plaquenil AAO Screening Guidelines for Plaquenil. by S P. Check out my recent review/summary of the American Academy of Ophthalmology’s statement on the Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy 2016 Revision from the Ophthalmology Journal 2016;186-1394.

    Is Damage Still Occurring? - Review of Optometry