It typically happens in the evening or nighttime hours when you're sitting or lying down. Restless legs syndrome, also known as Willis-Ekbom disease, can begin at any age and generally worsens as you age. It can disrupt sleep, which interferes with daily activities. Buy plaquenil uk Volume of distribution of chloroquine Can plaquenil cause pancreatitis Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. I am also suffering from RA and fibromyalgia. My legs and arms also feel very heavy and numb at times. I try to accomplish one goal a day, and maybe more if I can. I am taking Humira and Plaquenil for the RA and Lyrica for the fibromyalgia. They seem to help, but of course I have good days and bad days. Medications also help many people with symptoms as abnormal, unpleasant sensations in their legs or feet. They do, however, consistently describe the desire to move their legs. Sometimes, symptoms disappear for periods of time, then come back. Simple self-care steps and lifestyle changes may help relieve symptoms. The sensations, which generally occur within the limb rather than on the skin, are described as: usually don't describe the condition as a muscle cramp or numbness. Plaquenil heavy legs Hydroxychloroquine Uses, Dosage & Side Effects -, Plaquenil Side Effects Common, Severe, Long Term - Chloroquine hemolytic anemiaHow to taper off plaquenilPlaquenil et soleil I too have that 'heavy' feeling in my legs where it feels almost as if you won't be able to pick up your feet and so tend to shuffle. Going up steps is very difficult as some days it is easier to move one leg than the other. I don't, however, have to be standing a lot for this to happen. Heavy Legs feeling - Lupus - Inspire. Arm and leg heaviness" Rheumatoid Arthritis Community.. Restless legs syndrome - Symptoms and causes - Mayo Clinic. I have severe muscle spasms that seem like seizures & the jerking gets real bad at times, I can t stand very long or walk for more than 10 min tops on a good day. The weakness at times leaves me bedridden and my legs feel heavy most the time which makes it difficult to walk. Jun 25, 2013 hydroxychloroquine is the generic form of Plaquenil but the side effects are the same. My thigh muscles are so sore I can hardly walk, sit or stand. Stairs are a TRUE challenge. I have to struggle up and down taking only one step at a time using only one leg at a time. I have been on 400 mg daily of Plaquenil, last week my doctor took me off of it ue to increase in the pain I had been having in lower back and unbelievable pain in my left leg and especially the extreme pain in the heel of my left foot. It was becoming painful to walk. After 5 days of stopping pain was 80% better.