It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Can plaquenil cause insomnia Plaquenil table Plaquenil safe dosage The Plaquenil is supposed to kick in in 3 to 6 months. I think it was 8 months for me. One day I was congratulating myself for getting so many things done and I realised that the days had been getting better without my noticing. In the beginning I also was on a low dose of prednisone, which helped until plaquenil kicked in. Hydroxychloroquine comes as a tablet to take by mouth. For prevention of malaria in adults, two tablets are usually taken once a week on exactly the same day of each week. The first dose is taken 1 to 2 weeks before traveling to an area where malaria is common, and then doses are continued for 8 weeks. Is it true that Plaquenil stays in your system for months after you discontinue using it? - I took it for a very short time, and I know it damaged my eyes, but everything I read says they have no proof of it hurting a persons eyes in a short amount of time. - Healthboards - Infectious Diseases - Lyme Disease Plaquenil Hydroxychloroquine comes as a tablet to take by mouth. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. How long does it take plaquenil to leave your system Treating Lupus with Anti-Malarial Drugs Johns Hopkins., Hydroxychloroquine MedlinePlus Drug Information Chloroquine vs atovaquonePlaquenil back painPlaquenil and alcohol consumptionChloroquine resistant salmonella Nov 05, 2016 How long does it take for Plaquenil to leave your system. Asked by Joyceagnes Updated 6 November 2016 Topics plaquenil, multiple sclerosis, systemic lupus erythematosus, system How long does it take for Plaquenil to leave your system.. Healthboards - Infectious Diseases - Lyme Disease Plaquenil. Hydroxychloroquine Side-effects, uses, time to work. Because Plaquenil is the kind of drug that builds up in the blood stream and tissues I suspect, it has a very long half life. Simple drugs like abx can take as much as a month to completely clear from the body. I have been taking methotrexate for 7 years and stopped taking it 3 weeks ago. I am wondering how long it takes before my system is totally clear of all methotrexate and any effects it may have on the system. This discussion is related to About how long does it take for Methotrexate to leave a person's system. The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity.