My worst symptoms so far have been raynauds, fatigue, telangiectasias , heart burn, and digital ulcers. I'm fortunate that my lungs have been unaffected up to this point but I'm worried that contracting the virus could cause fibrosis in the lungs and lead to ILD and PAH. Retinal toxicity and plaquenil aafp How to take plaquenil 200 mg In 2010 I was diagnosed with CREST syndrome after having test after test and seeing doctor after doctor over 2 years. It had been difficult to decide that the range of symptoms I had been suffering were worth investigating as they were all so innocuous individually. My main complaints were a constant feeling of nausea, Continue reading My story May 18, 2017 Limited scleroderma, also known as CREST syndrome, is one subtype of scleroderma — a condition whose name means "hardened skin." The skin changes associated with limited scleroderma typically occur only in the lower arms and legs, below the elbows and knees, and sometimes affect the face and neck. Carol F CREST Syndrome I feel so alone right now and it would be nice to talk with someone who understands what I am going through. For the last two years my hands and feet have been going numb. At first I really did not think much of it since I had had a three herniated disc cervical injury and thought it could have been from that. Anybody have any knowledge about this that they can share? I've been trying to do some research but haven't come up with any solid answers. Plaquenil crest syndrome Will you have Systemic sclerosis scleroderma with Plaquenil., Limited scleroderma - Symptoms and causes - Mayo Clinic Chloroquine toxicity of retinaPlaquenil reviews Undifferentiated connective tissue disease UCTD is an autoimmune disease that can affect several systems in the body. Connective tissue disease CTD is classified as undifferentiated CTD when signs and symptoms are consistent with a CTD, but do not fulfill the diagnostic or classification criteria for one of the previously defined CTDs for example, rheumatoid arthritis or lupus. Undifferentiated connective tissue disease Genetic and Rare Diseases.. Carol F CREST Syndrome - Sclero. Scleroderma Treatment General – Standard - Scleroderma.. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. What is Plaquenil? Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. Check the latest outcomes from 50,877 Plaquenil users, or browse all drugs. What is Systemic sclerosis scleroderma?