I've stopped Sulfa as I was experiencing a bad taste & smell, which may be caused by sulfa. After a while it wasn't as effective and I too was prescribed methotrexate alongside. I'm about to start MTX & am hoping that I wont have side effects with that! The side effects of the methotrexate for me were horrendous (chronic chest infections) and I'm now asthmatic as a result. Hydroxychloroquine used for Is hydroxychloroquine sulphate a steroid Methotrexate is often used in combination with other DMARDs. Conventional DMARDs that have been paired with methotrexate include sulfasalazine, hydroxychloroquine, cyclosporine, leflunomide and azathioprine. Methotrexate-Sulfasalazine-Hydroxychloroquine Drug These may include hives, itching, swelling, difficualty breathing, fever, chills, and changes in blood pressure. It is not a substitute for medical advice and treatment. Compare Methotrexate vs Sulfasalazine head-to-head with other drugs for uses, ratings, cost, side effects, interactions and more. Methotrexate rated 6.7/10 vs Sulfasalazine rated 5.7/10 in overall patient satisfaction. I had side effects from MTX, which largely wore off, but haven't had any problems with the Hydroxy or Sulpha. I refuse to take it now even if its my passport to biologic treatment. I started with MTX which worked, but not enough so the others were added in which has been better. Methotrexate hydroxychloroquine sulfasalazine Combination hydroxychloroquine and sulfasalazine - do., Methotrexate plaquenil sulfasalazine, sulfasalazine and. Chloroquine dna mobilityPlaquenil side effects sunlightHow to taper off plaquenilChloroquine pregnancyHydroxychloroquine and bloating Methotrexate may be sold under. The two most commonly used antimalarials in the treatment of psoriatic arthritis are Plaquenil. Azulfidine sulfasalazine. What are Traditional DMARDs? Psoriatic-. Methotrexate vs Sulfasalazine Comparison -. Sulfasalazine and Hydroxychloroquine • Versus Arthritis.. A combination of methotrexate and sulfasalazine for a mean of 24 months range 20-28 months. All 4 patients experienced clinical improvement, with a reduction in the number of involved joints and in morning stiffness. In all 3 patients who had previously taken methotrexate, we were able to reduce the dosage, and the prednisone Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications results of a two-year, randomized, double-blind, placebo-controlled trial, Taking methotrexate while taking sulfasalazine may increase side effects in your gut and stomach, especially nausea. Disclaimer Our goal is to provide you with the most relevant and current.