Increased sensitivity to sunlight is a side effect of many widely used prescription and over-the-counter drugs. Rapid and severe sunburns, hives, rashes and increased risk of skin cancer can result. Hydroxychloroquine monitoring requirements Plaquenil eye pain Oct of macular damage secondary to plaquenil toxicity Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. As the media has discussed, Sjogren's is an autoimmune disease that attacks the tear and salivary glands and generally results in widespread dryness in the body. In addition to dry eyes and mouth, this can result in difficulty breathing and problems with digestive and bowel function. Sep 11, 2014 Photosensitivity is a common side-effect of methotrexate, plaquenil, and NSAIDs such as celebrex or advil. Photosensitivity may also be a serious side-effect of anti-TNF drugs such as cimzia, enbrel, humira, remicade, and simponi, as well as sulfasalazine. Assorted antibiotics, sulfa drugs, cold and allergy medicines and pain killers are among the medications that can make people more vulnerable to sun and heat. Increased sensitivity to heat, which can lead to dehydration, is also a side effect of many common medications. Plaquenil and heat intolerance Heat Intolerance and Thyroid Disease, Why There's More to Sjogren's Syndrome The Dr. Oz Show Chloroquine and fertilityHydroxychloroquine and taltz for axspaChloroquine and hiv Photoallergic reactions are caused by the reaction of a topical ointment with UV radiation. Topical ointments are applied directly to the skin. Reactions may develop after one to 10 days of exposure but often recur within 24 to 48 hours of re-exposure. Photosensitivity Reaction With Certain Medications. Photosensitivity A Side Effect of RA Medications. Heat Intolerance -. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Summer heat brings on a flare, not just the sun. Sudden heat like getting into a hot automobile that has been in the sun with windows rolled up. One blast of heat and I have had a flare. I have had flares in Walmart with all the lights. Increased sensitivity to heat. WebMD Symptom Checker helps you find the most common symptom combinations and medical conditions related to increased sensitivity to heat. Click on the combination that matches your symptoms to find the conditions that may cause these problems.